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Article

Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides.

The Journal of biological chemistry - 12 Nov 2004

Grabiec Alina, Meng Guangxun, Fichte Sylvia, Bessler Wolfgang, Wagner Hermann, Kirschning Carsten J

Abstract excerpt

Toll-like receptors (TLRs) mediate activation of the immune system upon challenge with microbial agonists, components of disintegrating cells of the body, or metabolic intermediates of lipidic nature. Comparison of murine (m) and human (h) TLR2 primary sequences revealed 65% of identical residues within the extracellular domains in contrast to 84% in the intracellular domains. Comparative analysis of TLR2-driven...

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Identifiers

PMID: 15342637
DOI: 10.1074/jbc.M405311200

Genes

TLR2
CSK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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