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Cadherin-26 (CDH26) regulates airway epithelial cell cytoskeletal structure and polarity

12 Feb 2018

Abstract excerpt

Polarization of the airway epithelial cells (AECs) in the airway lumen is critical to the proper function of the mucociliary escalator and maintenance of lung health, but the cellular requirements for polarization of AECs are poorly understood. Using human AECs and cell lines, we demonstrate that cadherin-26 (CDH26) is abundantly expressed in differentiated AECs, localizes to the cell apices near ciliary...

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PMID: 29449961
DOI: 10.1038/s41421-017-0006-x

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