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Article

Gene polymorphisms of immunoregulatory cytokines and angiotensin-converting enzyme in Wegener's granulomatosis.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2001

Muraközy G, Gaede K I, Ruprecht B, Gutzeit O, Schürmann M, Schnabel A, Schlaak M, Gross W L, Müller-Quernheim J

Abstract excerpt

Wegener's granulomatosis is a granulomatous and vasculitic disease of unknown origin. Gene polymorphisms are known to affect phenotypes of numerous diseases. Polymorphisms within the angiotensin-converting enzyme (ACE), transforming growth factor-beta1 (TGF-beta1), and interleukin-10 (IL-10) genes are suspected to modify the course of granulomatous disorders. We examined whether the genotype frequencies of the...

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Source

Identifiers

PMID: 11715070
DOI: 10.1007/s001090100263

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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