Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patients with Wegener's granulomatosis.

The Journal of rheumatology - 1 Jul 2003

Zhou Yihua, Huang Deren, Farver Carol, Hoffman Gary S

Abstract excerpt

OBJECTIVE: Wegener's granulomatosis (WG) is an idiopathic inflammatory condition characterized by upper and lower airway involvement and often renal dysfunction. Sites of tissue injury include pleomorphic cell populations, and classically mononuclear cell infiltrates that may form granulomas. Vascular inflammation (i.e., vasculitis) is often but not always present. Because CCR5 and its ligands influence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Antineutrophil Cytoplasmic
Share to Chemokine CCL3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CCL4

Share to Chemokine CCL5

Share to Granulomatosis with Polyangiitis

Share to Macrophage Inflammatory Proteins

Share to Receptors, CCR5

Source

Identifiers

PMID: 12858455

Genes

CCR5
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patients with Wegener's granulomatosis.PMID 12858455Read ↗

A functionally relevant IRF5 haplotype is associated with reduced risk to Wegener's granulomatosis.Semantic proximity Read ↗

Complex genetics of Wegener granulomatosis.Semantic proximity Read ↗

Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.Semantic proximity Read ↗

IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis.Semantic proximity Read ↗

A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren's Syndrome and Alters Receptor Expression as well as Functional Response.Semantic proximity Read ↗

Functionally relevant variations of the interleukin-10 gene associated with antineutrophil cytoplasmic antibody-negative Churg-Strauss syndrome, but not with Wegener's granulomatosis.Semantic proximity Read ↗

Genetics of ANCA-associated Vasculitides.Semantic proximity Read ↗

Epidemiology of Wegener's granulomatosis: Lessons from descriptive studies and analyses of genetic and environmental risk determinants.Semantic proximity Read ↗

Heterogeneity of CD4 and CD8+ memory T cells in localized and generalized Wegener's granulomatosisSemantic proximity Read ↗

Chemokine receptor 5 (CCR5) delta 32 polymorphism in lupus nephritis: a large case-control study and meta-analysis.Semantic proximity Read ↗

Delta 32 mutation of the chemokine-receptor 5 gene in inflammatory bowel disease.Semantic proximity Read ↗

Predominance of mononuclear cells expressing the chemokine receptor CCR5 in synovial effusions of patients with different forms of arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.