Article
Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions.
Acta crystallographica. Section D, Biological crystallography - 1 Sept 2004
Qiu Xiayang, Janson Cheryl A
Abstract excerpt
A topic of current interest is engineering surface mutations in order to improve the success rate of protein crystallization. This report explores the possibility of using metal-ion-mediated crystal-packing interactions to facilitate rational design. Escherichia coli apo acyl carrier protein was chosen as a test case because of its high content of negatively charged carboxylates suitable for metal binding with...
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