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Article

Influence of key amino acid mutation on the active site structure and on folding in acetyl-CoA synthase: a theoretical perspective.

Chemical communications (Cambridge, England) - 18 May 2015

Greco Claudio, Ciancetta Antonella, Bruschi Maurizio, Kulesza Alexander, Moro Giorgio, Cosentino Ugo

Abstract excerpt

Ad hoc quantum chemical modeling of the acetyl-CoA synthase local structure and folding allowed us to identify an unprecedented coordination mode of histidine sidechain to protein-embedded metal ions.

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Identifiers

PMID: 25896878
DOI: 10.1039/c5cc01575h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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