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Article

Effective improvement of D-phenylglycine aminotransferase solubility by protein crystal contact engineering.

Journal of molecular microbiology and biotechnology - 1 Jan 2012

Chantarasiri Aiya, Meevootisom Vithaya, Isarangkul Duangnate, Wiyakrutta Suthep

Abstract excerpt

Structure-guided genetic engineering of D-phenylglycine aminotransferase (D-PhgAT) aimed at increasing protein solubility was attempted. In silico analyses predicted the Asn439 and Gln444 as highly solvent-exposed β-turn residues involved with protein crystal contact (CC) potential candidates for...

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Identifiers

PMID: 22832812
DOI: 10.1159/000339833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22832812-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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