Article
A neural-specific splicing event generates an active form of the Wiskott-Aldrich syndrome protein.
EMBO reports - 1 Sept 2004
Le Page Yann, Demay Florence, Salbert Gilles
Abstract excerpt
Actin polymerization is required for cellular events such as podosome, lamellipode or filopode formation in migrating cells, and members of the Wiskott-Aldrich syndrome protein (WASP) family have essential roles in regulating actin dynamics at the cell leading edge. However, WASP proteins need first to be activated in order to be able to target actin polymerization. Here, we show the occurrence of a...
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