Article
Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background.
Journal of virology - 1 Sept 2004
Shepard Robin N, Ornelles David A
Abstract excerpt
Species C human adenovirus mutants that fail to express open reading frame 3 of early region 4 (E4orf3) are phenotypically indistinguishable from the wild-type virus when evaluated in cells cultured in vitro. However, E4orf3 gene function has been productively studied in the context of additional viral mutations. This study identifies diverse roles for the E4orf3 protein that are evident in the absence of early...
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