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Article

Interleukin-7 promotes HIV persistence during antiretroviral therapy.

Blood - 23 May 2013

Vandergeeten Claire, Fromentin Rémi, DaFonseca Sandrina, Lawani Mariam B, Sereti Irini, Lederman Michael M, Ramgopal Moti, Routy Jean-Pierre, Sékaly Rafick-Pierre, Chomont Nicolas

Abstract excerpt

HIV persists in latently infected memory CD4(+) T cells during antiretroviral therapy (ART). When administered to HIV-infected subjects receiving suppressive ART, interleukin-7 (IL-7) increases the number of CD4(+) T cells by promoting their survival and proliferation. However, little is known about the impact of IL-7 on HIV persistence during ART. By isolating large numbers of CD4(+) T cells from HIV-infected...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23589672
DOI: 10.1182/blood-2012-11-465625
PMCID: PMC3663425

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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