Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of nickel-specific T cell lines from patients with allergic contact dermatitis: comparison of different protocols.

Clinical immunology and immunopathology - 1 Oct 1994

Bour H, Nicolas J F, Garrigue J L, Demidem A, Schmitt D

Abstract excerpt

Allergic contact dermatitis is a delayed-type hypersensitivity reaction, secondary to hapten-specific T lymphocyte activation in sensitized individuals. The present study reports on the establishment of T cell lines from peripheral blood mononuclear cells (PBMC) of nickel-allergic patients, initially cultured with nickel, IL-2, or PHA and IL-2. It was possible to derive hapten-specific T cell lines from the three...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-CD8 Ratio
Share to Cell Line
Share to Lymphocyte Activation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nickel

Share to Phenotype

Share to T-Lymphocytes

Source

Identifiers

PMID: 7923911
DOI: 10.1006/clin.1994.1180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of nickel-specific T cell lines from patients with allergic contact dermatitis: comparison of different protocols.PMID 7923911Read ↗

Patients with allergic contact dermatitis to nickel and nonallergic individuals display different nickel-specific T cell responses. Evidence for the presence of effector CD8+ and regulatory CD4+ T cells.Semantic proximity Read ↗

Mononuclear cell subsets in the nickel-allergic reaction in vitro and in vivo.Semantic proximity Read ↗

Characterization of processing requirements and metal cross‐reactivities in T cell clones from patients with allergic contact dermatitis to nickelSemantic proximity Read ↗

Nickel and DNCB induce CCR7 expression on human dendritic cells through different signalling pathways: role of TNF-alpha and MAPK.Semantic proximity Read ↗

Interleukin-4 promotes the expansion of skin-infiltrating lymphocytes from atopic dermatitis in vitro.Semantic proximity Read ↗

TCR Reactivity in Human Nickel Allergy Indicates Contacts with Complementarity-Determining Region 3 but Excludes Superantigen-Like RecognitionSemantic proximity Read ↗

Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis.Semantic proximity Read ↗

TRAV7-2*02 Expressing CD8+ T Cells Are Responsible for Palladium AllergySemantic proximity Read ↗

Discrimination of human CD4 T cell clones based on their reactivity with antigen-presenting T cells.Semantic proximity Read ↗

Modulation of phenotype, cytokine production and stimulatory function of CD34+-derived DC by NiCl(2) and SDS.Semantic proximity Read ↗

Surface phenotypes of human T cell lines generated after WGA- and PHA-stimulation.Semantic proximity Read ↗

Interleukin-2 dependent selective activation of porcine gamma delta T lymphocytes by an extract from the leaves of Acanthospermum hispidum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.