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Article

Detection of c-kit-activating mutations in gastrointestinal stromal tumors by high-resolution amplicon melting analysis.

American journal of clinical pathology - 1 Aug 2004

Willmore Carlynn, Holden Joseph A, Zhou Luming, Tripp Sheryl, Wittwer Carl T, Layfield Lester J

Abstract excerpt

High-resolution amplicon melting analysis was used to scan for c-kit-activating mutations in exons 9, 11, 13, and 17 in 29 neoplasms diagnosed as gastrointestinal stromal tumors (GISTs). Immunohistochemically, 7 of 29 did not show strong CD 17 positivity and might represent true smooth muscle tum...

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Identifiers

PMID: 15323137
DOI: 10.1309/4E6U-YBY6-2N2F-CA6N

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15323137-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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