Article
Intracellular cytokine profile of cord and adult blood monocytes.
Bone marrow transplantation - 1 May 2001
Brichard B, Varis I, Latinne D, Deneys V, de Bruyere M, Leveugle P, Cornu G
Abstract excerpt
Cord blood (CB) transplantations are associated with low graft-versus-host disease (GVHD). The pathophysiology of GVHD involves interaction and activation of different cell types, as lymphocytes and monocytes, and results in a cascade of cytokine production. After antigen or mitogen stimulation, CB monocytes release lower levels of cytokines than adult blood (AB) monocytes. In this study, the detection of...
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