Intracellular cytokine profile of cord and adult blood monocytes.

doi:10.1038/sj.bmt.1703037

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Article

Intracellular cytokine profile of cord and adult blood monocytes.

Bone marrow transplantation - 1 May 2001

Brichard B, Varis I, Latinne D, Deneys V, de Bruyere M, Leveugle P, Cornu G

Abstract excerpt

Cord blood (CB) transplantations are associated with low graft-versus-host disease (GVHD). The pathophysiology of GVHD involves interaction and activation of different cell types, as lymphocytes and monocytes, and results in a cascade of cytokine production. After antigen or mitogen stimulation, CB monocytes release lower levels of cytokines than adult blood (AB) monocytes. In this study, the detection of...

Topics

Cytokines
Fetal Blood
Flow Cytometry
Humans
Immunophenotyping
Interferon-gamma
Interleukin-1
Lymphocyte Subsets
Monocytes
Phenotype
Tuberculin
Tumor Necrosis Factor-alpha

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Open in PubMed

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PMID: 11438825
DOI: 10.1038/sj.bmt.1703037

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