Article
Analysis of genetic polymorphisms in CCR5, CCR2, stromal cell-derived factor-1, RANTES, and dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin in seronegative individuals repeatedly exposed to HIV-1.
The Journal of infectious diseases - 15 Sept 2004
Liu Huanliang, Hwangbo Yon, Holte Sarah, Lee Jean, Wang Chunhui, Kaupp Nicole, Zhu Haiying, Celum Connie, Corey Lawrence, McElrath M Juliana, Zhu Tuofu
Abstract excerpt
To determine the influence of host genetics on human immunodeficiency virus (HIV) type 1 infection, we examined 94 repeatedly exposed seronegative (ES) individuals for polymorphisms in multiple genes and compared the results with those for 316 HIV-1-seropositive and 425 HIV-1-seronegative individuals. The frequency of homozygous C-C chemokine receptor (CCR) 5- Delta 32 was higher in ES (3.2%) than in...
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