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Article

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

Breast cancer research : BCR - 1 Jan 2004

Sparks Rachel, Ulrich Cornelia M, Bigler Jeannette, Tworoger Shelley S, Yasui Yutaka, Rajan Kumar B, Porter Peggy, Stanczyk Frank Z, Ballard-Barbash Rachel, Yuan Xiaopu, Lin Ming Gang, McVarish Lynda, Aiello Erin J, McTiernan Anne

Abstract excerpt

INTRODUCTION: UDP-glucuronosyltransferase (UGT) and sulfotransferase (SULT) enzymes are involved in removing sex hormones from circulation. Polymorphic variation in five UGT and SULT genes - UGT1A1 ((TA)6/(TA)7), UGT2B4 (Asp458Glu), UGT2B7 (His268Tyr), UGT2B15 (Asp85Tyr), and SULT1A1 (Arg213His)--may be associated with circulating sex hormone concentrations, or the risk of an estrogen receptor-negative (ER-) or...

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Identifiers

PMID: 15318931
DOI: 10.1186/bcr818
PMCID: PMC549165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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