Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stable isotope aided nuclear magnetic resonance study to investigate the receptor-binding site of human interleukin 1 beta.

Biochemistry - 3 Mar 1992

Tate S, Kikumoto Y, Ichikawa S, Kaneko M, Masui Y, Kamogashira T, Ouchi M, Takahashi S, Inagaki F

Abstract excerpt

Resonance assignments for interleukin 1 beta at neutral pH were made by using three-dimensional NMR in combination with specific labeling and double-labeling methods with stable isotopes. On the basis of the present assignments, 15N single-quantum coherence spectra of N-terminal truncated and fusion mutants were compared with that of the wild-type. Although these mutants have reduced biological activity, they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Cricetinae

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrogen-Ion Concentration

Share to Molecular Sequence Data

Share to Mutation

Share to Protein Binding

Share to Protein Conformation

Source

Identifiers

PMID: 1531768
DOI: 10.1021/bi00123a032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stable isotope aided nuclear magnetic resonance study to investigate the receptor-binding site of human interleukin 1 beta.PMID 1531768Read ↗

Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.Semantic proximity Read ↗

Complete resonance assignment for the polypeptide backbone of interleukin 1 beta using three-dimensional heteronuclear NMR spectroscopy.Semantic proximity Read ↗

The insulin-like growth factor (IGF)binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis.Semantic proximity Read ↗

Synthetic alleles at position 121 define a functional domain of human interleukin-1 beta.Semantic proximity Read ↗

Structure, stability and biological properties of a N-terminally truncated form of recombinant human interleukin-6 containing a single disulfide bond.Semantic proximity Read ↗

Functional implications of interleukin-1 beta based on the three-dimensional structure.Semantic proximity Read ↗

Identification of key residues in the amino-terminal third of human interleukin-1 alpha.Semantic proximity Read ↗

A point mutation uncouples human interleukin-1 beta biological activity and receptor binding.Semantic proximity Read ↗

Refined solution structure of the C-terminal DNA-binding domain of human immunovirus-1 integrase.Semantic proximity Read ↗

Recombinant-derived interleukin-1 alpha stabilized against specific deamidation.Semantic proximity Read ↗

Importance of the carboxy-terminus of human interleukin-11 in conserving its biological activity.Semantic proximity Read ↗

Biophysical characterization of structural properties and folding of interleukin-1 receptor antagonist.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.