Complete resonance assignment for the polypeptide backbone of interleukin 1 beta using three-dimensional heteronuclear NMR spectroscopy.

doi:10.1021/bi00466a018

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Article

Complete resonance assignment for the polypeptide backbone of interleukin 1 beta using three-dimensional heteronuclear NMR spectroscopy.

Biochemistry - 10 Apr 1990

Driscoll P C, Clore G M, Marion D, Wingfield P T, Gronenborn A M

Abstract excerpt

The complete sequence-specific assignment of the 15N and 1H backbone resonances of the NMR spectrum of recombinant human interleukin 1 beta (153 residues, Mr = 17,400) has been obtained by using primarily 15N-1H heteronuclear three-dimensional (3D) NMR techniques in combination with 15N-1H hetero...

Topics

Amides
Amino Acid Sequence
Humans
Hydrogen
Interleukin-1
Magnetic Resonance Spectroscopy
Molecular Sequence Data
Mutation
Nitrogen Isotopes
Protein Conformation
Recombinant Proteins

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