Article
H6D polymorphism in macrophage-inhibitory cytokine-1 gene associated with prostate cancer.
Journal of the National Cancer Institute - 18 Aug 2004
Lindmark Fredrik, Zheng S Lilly, Wiklund Fredrik, Bensen Jeannette, Bälter Katarina Augustsson, Chang Baoli, Hedelin Maria, Clark Jonathan, Stattin Pär, Meyers Deborah A, Adami Hans-Olov, Isaacs William, Grönberg Henrik, Xu Jianfeng
Abstract excerpt
BACKGROUND: Accumulating epidemiologic and molecular evidence suggest that inflammation is an important component in the etiology of prostate cancer. Macrophage-inhibitory cytokine-1 (MIC-1), a member of the transforming growth factor beta superfamily, is thought to play an important role in inflammation by regulating macrophage activity. We examined whether sequence variants in the MIC-1 gene are associated with...
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