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Article

Macrophages from lupus-prone MRL mice are characterized by abnormalities in Rho activity, cytoskeletal organization, and adhesiveness to extracellular matrix proteins.

Journal of leukocyte biology - 1 Nov 2004

Longacre Angelika, Koh Jason S, Hsiao Kevin K-H, Gilligan Hannah, Fan Hanli, Patel Vimal A, Levine Jerrold S

Abstract excerpt

Macrophages (mphi) from prediseased mice of the major murine models of lupus have an identical defect in cytokine expression that is triggered by serum and/or apoptotic cells. It is striking that cytokine expression in the absence of serum and apoptotic cells is equivalent to that of nonautoimmun...

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Source

Identifiers

PMID: 15316033
DOI: 10.1189/jlb.0604346

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15316033-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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