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Article

A myocardin-related transcription factor regulates activity of serum response factor in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 24 Aug 2004

Han Zhe, Li Xiumin, Wu Jiang, Olson Eric N

Abstract excerpt

Serum response factor (SRF) regulates genes involved in cell proliferation, migration, cytoskeletal organization, and myogenesis. Myocardin and myocardin-related transcription factors (MRTFs) act as powerful transcriptional coactivators of SRF in mammalian cells. We describe an MRTF from Drosophila, called DMRTF, which shares high homology with the functional domains of mammalian myocardin and MRTFs. DMRTF forms...

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Identifiers

PMID: 15314239
DOI: 10.1073/pnas.0405085101
PMCID: PMC515097

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A myocardin-related transcription factor regulates activity of serum response factor in Drosophila.PMID 15314239Read ↗

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal developmentSemantic proximity Read ↗

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