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Article

A myocardin-related transcription factor regulates activity of serum response factor in Drosophila.

Proceedings of the National Academy of Sciences of the United States of America - 24 Aug 2004

Han Zhe, Li Xiumin, Wu Jiang, Olson Eric N

Abstract excerpt

Serum response factor (SRF) regulates genes involved in cell proliferation, migration, cytoskeletal organization, and myogenesis. Myocardin and myocardin-related transcription factors (MRTFs) act as powerful transcriptional coactivators of SRF in mammalian cells. We describe an MRTF from Drosophi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15314239
DOI: 10.1073/pnas.0405085101
PMCID: PMC515097

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15314239-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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A myocardin-related transcription factor regulates activity of serum response factor in Drosophila.PMID 15314239Read ↗

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal developmentSemantic proximity Read ↗

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Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.Semantic proximity Read ↗

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