Article
MCP-1 in Alzheimer's disease patients: A-2518G polymorphism and serum levels.
Neurobiology of aging - 1 Oct 2004
Fenoglio Chiara, Galimberti Daniela, Lovati Carlo, Guidi Ilaria, Gatti Alberto, Fogliarino Sergio, Tiriticco Marco, Mariani Claudio, Forloni Gianluigi, Pettenati Carla, Baron Pierluigi, Conti Giancarlo, Bresolin Nereo, Scarpini Elio
Abstract excerpt
MCP-1 levels are increased in CSF of patients with Alzheimer's disease (AD) compared with controls, suggesting a role in the development of dementia. Recently, a biallelic A/G polymorphism in the MCP-1 promoter at position -2518 has been found, influencing the level of MCP-1 expression in respons...
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