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IL-1β, IL-6, IL-10, and TNFα single nucleotide polymorphisms are associated with cerebrospinal fluid levels of biomarkers of Alzheimer’s disease

2019-11-14

Abstract excerpt

<title>Abstract</title> <p>Background Neuroinflammation plays an important role in Alzheimer’s disease (AD). During this process, activated microglia release pro-inflammatory cytokines such as interleukin (IL)-1α, IL-1β, IL-6 and tumor necrosis factor α (TNFα) that participate in neuron damage. However, anti-inflammatory cytokines (such as IL-10), which maintain homeostasis of immune response, are also released....

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Literature Corpus work
b2977c1a-79df-5862-acb6-5a187f1fa166
DOI
10.21203/rs.2.17198/v1
Open publication

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