Article
Length and somatic mosaicism of CAG and GGN repeats in the androgen receptor gene and the risk of prostate cancer in men with benign prostatic hyperplasia.
Annals of Saudi medicine - 1 Jan 2000
Tayeb Mohammed T, Clark Caroline, Murray Graeme I, Sharp Linda, Haites Neva E, McLeod Howard L
Abstract excerpt
BACKGROUND: The most common malignancy in men worldwide is cancer of the prostate and determinants of prostate cancer (PRCa) risk remain largely unidentified. Many candidate genes may be involved in PRCa, such as those that are central to cellular growth and differentiation in the prostate gland. We analysed the polymorphic CAG and GGN repeats sequence in exon 1 of the AR gene to determine if the number of...
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