Article
Tandem CAG repeats of the androgen receptor gene and prostate cancer risk in black and white men.
Endocrine - 1 Jul 2001
Panz V R, Joffe B I, Spitz I, Lindenberg T, Farkas A, Haffejee M
Abstract excerpt
The most common malignancy in men worldwide is cancer of the prostate. Androgens play a direct role in normal and malignant growth of prostate cells via the androgen receptor (AR). This study analyzed the polymorphic CAG repeat sequence in exon 1 of the AR gene to determine if the number of repeats might be an indicator of prostate cancer risk or aggressive disease. DNA was extracted from blood samples of 20...
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