Article
Polymorphic repeats in the androgen receptor gene in high-risk sibships.
The Prostate - 1 Aug 2001
Miller E A, Stanford J L, Hsu L, Noonan E, Ostrander E A
Abstract excerpt
BACKGROUND: Genetic susceptibility may explain some familial clusters of prostate cancer. The polymorphic androgen receptor (AR) gene, which mediates androgen activity in the prostate, is a candidate gene that may influence predisposition to the disease. METHODS: We analyzed the polymorphic (CAG)n and (GGN)n repeats within the AR gene in men from 51 high-risk prostate cancer sibships, which included at least one...
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