Article
CYP3A4 promoter variant is associated with prostate cancer risk in men with benign prostate hyperplasia.
Oncology reports - 1 Jan 2000
Tayeb Mohammed T, Clark Caroline, Sharp Linda, Haites Neva E, Rooney Patrick H, Murray Graeme I, Payne Simon N L, McLeod Howard L
Abstract excerpt
Prostate cancer (PRCa) is one of the most common causes of cancer death in men and determinants of PRCa risk remain largely unidentified. Benign prostatic hyperplasia (BPH) is found in the majority of ageing men and has been linked with PRCa. CYP3A4 may influence PRCa through its role in testosterone metabolism. This nested case-control study assessed a CYP3A4 single nucleotide polymorphism as a risk factor for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.