Article
Oxidized low-density lipoprotein, iron stores, and haptoglobin polymorphism.
Atherosclerosis - 1 Sept 2004
Brouwers Annelies, Langlois Michel, Delanghe Joris, Billiet Johan, De Buyzere Marc, Vercaemst Raf, Rietzschel Ernst, Bernard Dirk, Blaton Victor
Abstract excerpt
BACKGROUND: In vitro experimental studies demonstrated that iron promotes free radical-induced low-density lipoprotein (LDL) oxidation. OBJECTIVE: To test the hypothesis that circulating oxidized LDL (oxLDL) levels might be associated with body iron stores (serum ferritin) and iron-related genetic markers (hemochromatosis gene C282Y mutation, haptoglobin polymorphism). METHODS: We investigated 381 (176 males, 205...
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