Article
The haptoglobin 2-2 phenotype affects serum markers of iron status in healthy males.
Clinical chemistry - 1 Oct 2000
Langlois M R, Martin M E, Boelaert J R, Beaumont C, Taes Y E, De Buyzere M L, Bernard D R, Neels H M, Delanghe J R
Abstract excerpt
BACKGROUND: Human iron status is influenced by environmental and genetic factors. We hypothesized that the genetic polymorphism of haptoglobin (Hp), a hemoglobin-binding plasma protein, could affect iron status. METHODS: Reference values of serum iron status markers were compared according to Hp phenotypes (Hp 1-1, Hp 2-1, Hp 2-2; determined by starch gel electrophoresis) in 717 healthy adults. Iron storage was...
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