Article
IDDM2 and the polymorphism of the human tyrosine hydroxylase (hTH) gene in African Americans with type-1 diabetes.
Journal of the National Medical Association - 1 Aug 2004
Berka Noureddine, Nunlee-Bland Gail, Erabhaoui Elhajja, Belmamoun Maher, Dunston Georgia M
Abstract excerpt
In this study, we investigate the polymorphic microsatellite repeat (TCAT)n, in the insulin gene region that has been associated with susceptibility to type-1 diabetes in some Caucasian populations. The microsatellite repeat polymorphism begins at base pair 1,170 in intron 1 of the hTH gene, which is located on the short arm of chromosome 11. This study is the first to investigate the association of this...
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