Article
Tyrosine hydroxylase gene microsatellite polymorphism associated with insulin resistance in depressive disorder.
Metabolism: clinical and experimental - 1 Sept 2000
Chiba M, Suzuki S, Hinokio Y, Hirai M, Satoh Y, Tashiro A, Utsumi A, Awata T, Hongo M, Toyota T
Abstract excerpt
A high association between type 2 diabetes mellitus and depressive illness has been reported. Insulin resistance during depressive illness might contribute to the linkage between depression and type 2 diabetes. To determine whether the genetic polymorphisms of the tyrosine hydroxylase ([TH] HUMTH01) and insulin (INS-VNTR) genes contribute to insulin resistance in depressive illness, we analyzed the association...
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