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Article

Phenotype and Response to PAMPs of Human Monocyte-Derived Foam Cells Obtained by Long-Term Culture in the Presence of oxLDLs.

Frontiers in immunology - 1 Jan 2020

Nogieć Anna, Bzowska Małgorzata, Demczuk Agnieszka, Varol Chen, Guzik Krzysztof

Abstract excerpt

Cholesterol-laden, foam macrophages constitute the most characteristic component of human atherosclerotic plaques. Persistent uptake of oxLDLs results in accumulation of lipid bodies inside the cells and determines their phenotype and subsequent functions. In this work, we describe the phenotype of human monocyte-derived foam cells obtained by differentiation in the constant presence of oxLDLs for 30 days...

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Source

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Identifiers

PMID: 32849539
DOI: 10.3389/fimmu.2020.01592
PMCID: PMC7417357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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