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Article

RUNX2 (6p21.1) amplification in osteosarcoma.

Human pathology - 1 Dec 2019

Gupta Sounak, Ito Tatsuo, Alex Deepu, Vanderbilt Chad M, Chang Jason C, Islamdoust Nasrin, Zhang Yanming, Nafa Khedoudja, Healey John, Ladanyi Marc, Hameed Meera R

Abstract excerpt

Prior cytogenetic profiling of osteosarcomas has suggested that amplifications at the 6p12-21 locus are relatively common alterations in these tumors. However, these studies have been limited by variable testing methodologies used as well as by the relatively small numbers of cases that have been analyzed. To better define the frequency of this alteration, 111 osteosarcomas were profiled using hybridization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31669178
DOI: 10.1016/j.humpath.2019.09.010
PMCID: PMC7053429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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