Article
Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAA receptor beta3 subunit genes.
Psychiatry research - 15 Jul 2004
Young Ross McD, Lawford Bruce R, Feeney Gerald F X, Ritchie Terry, Noble Ernest P
Abstract excerpt
Molecular genetic research has identified promising markers of alcohol dependence, including alleles of the D2 dopamine receptor (DRD2) and the GABAA receptor beta3 subunit (GABRB3) genes. Whether such genetic risk manifests itself in stronger alcohol-related outcome expectancies, or in difficulty resisting alcohol, is unknown. In the present study, A1+ (A1A1 and A1A2 genotypes) and A1- (A2A2 genotype) alleles of...
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