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Article

A crucial interaction between embryonic red blood cell progenitors and paraxial mesoderm revealed in spadetail embryos.

Developmental cell - 1 Aug 2004

Rohde Laurel A, Oates Andrew C, Ho Robert K

Abstract excerpt

Zebrafish embryonic red blood cells (RBCs) develop in trunk intermediate mesoderm (IM), and early macrophages develop in the head, suggesting that local microenvironmental cues regulate differentiation of these two blood lineages. spadetail (spt) mutant embryos, which lack trunk paraxial mesoderm (PM) due to a cell-autonomous defect in tbx16, fail to produce embryonic RBCs but retain head macrophage development....

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Identifiers

PMID: 15296721
DOI: 10.1016/j.devcel.2004.07.010
PMCID: PMC2801434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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