Article
TRA-1/GLI controls development of somatic gonadal precursors in C. elegans.
Development (Cambridge, England) - 1 Sept 2004
Mathies Laura D, Schvarzstein Mara, Morphy Kristin M, Blelloch Robert, Spence Andrew M, Kimble Judith
Abstract excerpt
TRA-1/GLI is best known as a master regulator of sex determination in the nematode C. elegans, but its fly and vertebrate homologs (e.g. Ci, GLI) regulate embryonic patterning and cell proliferation. In this paper, we show that TRA-1/GLI controls development of the two somatic gonadal precursors (SGPs) in both XX and XO animals, in addition to its role in sex determination. Normally, SGPs reside at the poles of...
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