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Article

C. elegans HIM-8 functions outside of meiosis to antagonize EGL-13 Sox protein function.

Developmental biology - 15 May 2006

Nelms Brian L, Hanna-Rose Wendy

Abstract excerpt

egl-13 encodes a Sox domain protein that is required for proper uterine seam cell development in Caenorhabditis elegans. We demonstrate that mutations of the C2H2 zinc fingers encoded by the him-8 (high incidence of males) gene partially suppress the egg-laying and connection-of-gonad morphology defects caused by incompletely penetrant alleles of egl-13. him-8 alleles have previously characterized recessive...

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PMID: 16546157
DOI: 10.1016/j.ydbio.2006.02.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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C. elegans HIM-8 functions outside of meiosis to antagonize EGL-13 Sox protein function.PMID 16546157Read ↗

Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans.Semantic proximity Read ↗

HIM-8 binds to the X chromosome pairing center and mediates chromosome-specific meiotic synapsis.Semantic proximity Read ↗

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COG-2, a sox domain protein necessary for establishing a functional vulval-uterine connection in Caenorhabditis elegans.Semantic proximity Read ↗

TRA-1/GLI controls development of somatic gonadal precursors in C. elegans.Semantic proximity Read ↗

C. elegans HIM-17 links chromatin modification and competence for initiation of meiotic recombination.Semantic proximity Read ↗

Antagonism between MES-4 and Polycomb repressive complex 2 promotes appropriate gene expression in C. elegans germ cells.Semantic proximity Read ↗

Identification of chromosome sequence motifs that mediate meiotic pairing and synapsis in C. elegans.Semantic proximity Read ↗

A germ cell determinant reveals parallel pathways for germ line development in Caenorhabditis elegans.Semantic proximity Read ↗

The transcription factor LSL-1 interacts with the chromatin factors HIM-17, XND-1 and BRA-2 to promote the germline-specific transcriptional repertoire and to safeguard germ cell fate in <i>C. elegans</i>Semantic proximity Read ↗

Mutations in Caenorhabditis elegans him-19 show meiotic defects that worsen with age.Semantic proximity Read ↗

The zinc-finger transcription factor LSL-1 is a major regulator of the germline transcriptional program in <i>C. elegans</i>Semantic proximity Read ↗

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