Article
Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates.
Journal of bacteriology - 1 Aug 2004
Baquero María-Rosario, Nilsson Annika I, Turrientes María del Carmen, Sandvang Dorthe, Galán Juan Carlos, Martínez Jose Luís, Frimodt-Møller Niels, Baquero Fernando, Andersson Dan I
Abstract excerpt
Polymorphisms in the rifampin resistance mutation frequency (f) were studied in 696 Escherichia coli strains from Spain, Sweden, and Denmark. Of the 696 strains, 23% were weakly hypermutable (4 x 10(-8) < or = f < 4 x 10(-7)), and 0.7% were strongly hypermutable (f > or = 4 x 10(-7)). Weak mutators were apparently more frequent in southern Europe and in blood isolates (38%) than in urinary tract isolates (25%)...
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