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Article

Prevalence of hypermutator isolates of Achromobacter spp. from cystic fibrosis patients.

International journal of medical microbiology : IJMM - 1 Feb 2020

Ridderberg Winnie, Jensen Handberg Kurt, Nørskov-Lauritsen Niels

Abstract excerpt

Bacteria colonising the lungs of cystic fibrosis (CF) patients encounter high selective pressures. Hypermutation facilitates adaptation to fluctuating environments, and hypermutator strains are frequently isolated from CF patients. We investigated the prevalence of hypermutator isolates of Achromobacter spp. among patients affiliated with the CF Centre in Aarhus, Denmark. By exposure to rifampicin, the mutation...

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PMID: 31969255
DOI: 10.1016/j.ijmm.2020.151393

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