Article
Intrapopulation variability in mutator prevalence among urinary tract infection isolates of Escherichia coli.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Jun 2016
Couce A, Alonso-Rodriguez N, Costas C, Oliver A, Blázquez J
Abstract excerpt
Bacteria with elevated mutation rates represent a risk factor for treatment failure and are often found with high frequency in clinical isolates from different sources. How this frequency reflects the among-population and within-population proportion of hypermutators is unknown, despite its importance to the choice of antibiotic therapies that minimize the likelihood of resistance development. Here we screened...
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