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Article

Escherichia coli mutators present an enhanced risk for emergence of antibiotic resistance during urinary tract infections.

Antimicrobial agents and chemotherapy - 1 Jan 2004

Miller Keith, O'Neill Alexander John, Chopra Ian

Abstract excerpt

Mutators may present an enhanced risk for the emergence of antibiotic resistance in bacteria during chemotherapy. Using Escherichia coli mutators as a model, we evaluated their ability to develop resistance to antibiotics routinely used for the treatment of urinary tract infections (UTIs). Under conditions that simulate therapeutic drug concentrations in humans, low-level resistance to trimethoprim, gentamicin,...

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Identifiers

PMID: 14693514
DOI: 10.1128/AAC.48.1.23-29.2004
PMCID: PMC310165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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