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Article

Increased mutability to fosfomycin resistance in Proteus mirabilis clinical isolates.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2018

Fonseca Marina R B, Sato Juliana L, Lima-Noronha Marco A, Migliorini Letícia B, Fernández-Silva Frank S, Galhardo Rodrigo S

Abstract excerpt

In the present study, we screened a collection of 77 Proteus mirabilis clinical isolates for the presence of mutators, using the frequency of both rifampicin and fosfomycin resistance mutants as markers of spontaneous mutagenesis. We found that none of the strains in our collection are mutators for the rifampicin resistance (RifR) marker. Nevertheless, a significant fraction of the isolates (17%) show high...

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Identifiers

PMID: 29248795
DOI: 10.1016/j.meegid.2017.12.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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