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Article

Effect of thymidylate synthase gene polymorphism on the response to chemotherapy and clinical outcome of non-small cell lung cancer patients.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2015

Dong Honglin, Bao Dengke, Guo Xu, Hu Jie, Li Xiaofei, Wan Shaogui, Xing Jinliang

Abstract excerpt

Genetic polymorphisms of thymidylate synthase (TYMS) gene have been reported to be associated with development or prognosis of several cancers. However, the association between polymorphisms of TYMS gene and clinical outcomes of non-small cell lung cancer (NSCLC) patients are still unknown. In the present study, we investigated the associations between single nucleotide polymorphisms (SNPs) of TYMS gene and...

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Identifiers

PMID: 25877757
DOI: 10.1007/s13277-015-3447-6

Genes

TYMS

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