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Article

Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis.

Analytical chemistry - 1 Aug 2004

Ekstrøm Per O, Bjørge Tone, Dørum Anne, Longva Ane Sager, Heintz Karen-Marie, Warren David J, Hansen Svein, Gislefoss Randi Elin, Hovig Eivind

Abstract excerpt

Analysis of DNA variation in biological samples most frequently utilizes the polymerase chain reaction (PCR) performed on extracted genomic DNA, followed by visualization of alleles using various methodologies. Few reports have demonstrated that amplification of DNA from plasma and serum samples is possible. We have performed DNA amplification on a large set of serum samples (n = 2955). Here, we report that known...

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Identifiers

PMID: 15283579
DOI: 10.1021/ac049788k

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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