GATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B gene

Abstract excerpt

Expression of Gfi (growth factor-independence)-1B, a Gfi-1-related transcriptional repressor, is restricted to erythroid lineage cells and is essential for erythropoiesis. We have determined the transcription start site of the human Gfi-1B gene and located its first non-coding exon approximately 7.82 kb upstream of the first coding exon. The genomic sequence preceding this first non-coding exon has been...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blood disorders and treatments
• Share to Erythrocyte Function and Pathophysiology
• Share to Immunodeficiency and Autoimmune Disorders