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Article

Structure and function of the mitochondrial genome.

Journal of inherited metabolic disease - 1 Jan 1992

Clayton D A

Abstract excerpt

It is now clear that molecular defects in human mitochondrial DNA play a significant role in human disease. Mitochondrial DNA mutations range from single base changes in the 16.5 kilobase-pair genome up to large deletions and rearrangements. Independently of the actual cause of a given mutation,...

Topics

Animals
DNA Replication
DNA, Mitochondrial
Gene Expression
Genetic Diseases, Inborn
Humans
Mutation
Transcription, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1528004
DOI: 10.1007/BF01799602

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1528004-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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