Article
The pathophysiology of mitochondrial biogenesis: towards four decades of mitochondrial DNA research.
Molecular genetics and metabolism - 1 Nov 2000
Fernández-Moreno M A, Bornstein B, Petit N, Garesse R
Abstract excerpt
Mitochondria are with very few exceptions ubiquitous organelles in eukaryotic cells where they are essential for cell life and death. Mitochondria play a central role not only in a variety of metabolic pathways including the supply of the bulk of cellular ATP through oxidative phosphorylation (OXPHOS), but also in complex processes such as development, apoptosis, and aging. Mitochondria contain their own genome...
Topics
- Animals
- Base Sequence
- DNA, Mitochondrial
- Disease Models, Animal
- Humans
- Mitochondria
- Mitochondrial Myopathies
- Molecular Sequence Data
- Mutation