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Mitochondrial Gene Expression and Beyond-Novel Aspects of Cellular Physiology.

Cells - 19 Dec 2019

Kotrys Anna V, Szczesny Roman J

Abstract excerpt

Mitochondria are peculiar organelles whose proper function depends on the crosstalk between two genomes, mitochondrial and nuclear. The human mitochondrial genome (mtDNA) encodes only 13 proteins; nevertheless, its proper expression is essential for cellular homeostasis, as mtDNA-encoded proteins are constituents of mitochondrial respiratory complexes. In addition, mtDNA expression results in the production of...

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PMID: 31861673
DOI: 10.3390/cells9010017
PMCID: PMC7017415

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Source receipt: pubmed, retrieved 7 Sept 2026.

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