Mitochondrial DNA: Unraveling the "other" genome.

doi:10.1097/JXX.0000000000000646

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Article

Mitochondrial DNA: Unraveling the "other" genome.

Journal of the American Association of Nurse Practitioners - 1 Sept 2021

Heuer Beth

Abstract excerpt

ABSTRACT: The mitochondrial genome, which contains all of the hereditary information within human mitochondria, consists of 16,569 base pairs of double-stranded DNA that encode 37 genes. Pathogenic mutations of mitochondrial DNA (mtDNA) cause dysfunction of the respiratory chain and the process of oxidative phosphorylation (OXPHOS), leading to impaired adenosine triphosphate synthesis. Nuclear DNA (nDNA)...

Topics

DNA, Mitochondrial
Humans
Mitochondria
Mitochondrial Diseases
Mutation
Oxidative Phosphorylation

Source

Open in PubMed

Identifiers

PMID: 34491238
DOI: 10.1097/JXX.0000000000000646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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