Article
Scd1ab-Xyk: a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse.
Molecular genetics and genomics : MGG - 1 Sept 2004
Lu Y, Bu L, Zhou S, Jin M, Sundberg J P, Jiang H, Qian M, Shi Y, Zhao G, Kong X, Hu L
Abstract excerpt
We describe here a spontaneous, autosomal recessive mutant mouse suffering from skin and hair defects, which arose in the outbred Kunming strain. By haplotype analysis and direct sequencing of PCR products, we show that this mutation is a new allele of the asebia locus with a naturally occurring mutation in the Scd1 gene (a CCC insertion at nucleotide position 835 in exon 5), which codes for stearoyl-CoA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.