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Article

Genetic characterization of a mouse line with primary aldosteronism.

Journal of molecular endocrinology - 1 Feb 2017

Perez-Rivas L G, Rhayem Y, Sabrautzki S, Hantel C, Rathkolb B, Hrabě de Angelis M, Reincke M, Beuschlein F, Spyroglou A

Abstract excerpt

In an attempt to define novel genetic loci involved in the pathophysiology of primary aldosteronism, a mutagenesis screen after treatment with the alkylating agent N-ethyl-N-nitrosourea was established for the parameter aldosterone. One of the generated mouse lines with hyperaldosteronism was phenotypically and genetically characterized. This mouse line had high aldosterone levels but normal creatinine and urea...

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Identifiers

PMID: 27965370
DOI: 10.1530/JME-16-0200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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